The Reliability of Some Biochemical and Haematological Parameters in Predicting Uncomplicated Malaria Parasite Infection among Children in Anambra State, Nigeria

Autor: Joseph Effiong Eyo, Ononye Benjamin Uzonna, Chukwuebuka Uzochukwu Uzochukwu, O. P. Okeke, Fabian Chukwuemenam Okafor, N. P. Udeh, Amana Gabriel Unekwu, Maduabuchi Isaac Aniekwe, C. A. Imakwu
Rok vydání: 2020
Předmět:
Zdroj: International Journal of TROPICAL DISEASE & Health. :45-52
ISSN: 2278-1005
DOI: 10.9734/ijtdh/2020/v41i2230411
Popis: Malaria remains endemic in Sub-Saharan Africa. Haematological and biochemical changes that occur have been suggested as potential predictors of malaria. This study was aimed at evaluating the diagnostic relevance of some haematological and biochemical parameters in predicting malaria in children in Anambra State, Nigeria. A cross-sectional study involving 248 symptomatic and asymptomatic children in Anambra State, Nigeria was conducted. Thin blood films were prepared for each subject and stained with Giemsa to aid the detection of malaria parasites. Their haematological and biochemical parameters were determined. Haematological and biochemical parameters of infected and uninfected children from the communities and hospitals were compared using the Student’s t-test. Difference was set at p0.05). The comparison of the biochemical and haematological indices, and the parasite density of infected and uninfected children from communities and hospitals in Anambra State, Nigeria showed that all the haematological indices except WBC of hospital and community infection did not differ significantly (p> 0.05), but there were significant differences in their Na+, total iron, SGPT and SGOT. The comparison of these results showed that the changes in serum levels of these parameters may not be associated with malaria infection.
Databáze: OpenAIRE