Liposomal Vincristine: The Central Role of Drug Retention in Defining Therapeutically Optimized Anticancer Formulations
| Autor: | Pieter R. Cullis, Marcel B. Bally, Nancy Boman, Lawrence D. Mayer, Murray S. Webb |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Drug
Vincristine Vinca Childhood leukemia biology business.industry media_common.quotation_subject Alkaloid Pharmacology medicine.disease biology.organism_classification Liposomal vincristine hemic and lymphatic diseases Neuroblastoma medicine Cancer research business Rhabdomyosarcoma medicine.drug media_common |
| Zdroj: | Long Circulating Liposomes: Old Drugs, New Therapeutics ISBN: 9783662221174 |
| Popis: | Vincristine is an alkaloid derived from Vinca rosea that is effective against a wide variety of human carcinomas.1,2 When used in conjunction with corticosteroids, vincristine is the treatment of choice to induce remissions in childhood leukemia. Vincristine is also part of a complex protocol used in the treatment of adult patients with Hodgkin’s disease or non-Hodgkin’s lymphomas. In addition, vincristine has some effectiveness against Wilms’ tumor, neuroblastoma, brain tumors, rhabdomyosarcoma, and carcinomas of the breast and the bladder, as well as the male and female reproductive systems. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|