ChemInform Abstract: Stereospecific Ring Expansion of Chiral Vinyl Aziridines

Autor:	Mauricio Navarro Villalobos, Jon T. Njardarson, Matthew Brichacek, Alexandra Plichta
Rok vydání:	2011
Předmět:	chemistry.chemical_compound Stereospecificity chemistry Stereochemistry Feature (computer vision) General Medicine Aziridine Ring (chemistry) Pyrrole derivatives
Zdroj:	ChemInform. 42
ISSN:	0931-7597
DOI:	10.1002/chin.201123092
Popis:	In this report, it is demonstrated that chiral vinyl aziridines can be stereospecifically ring expanded. This synthetic approach allows controlled access to chiral 2,5-cis- or 2,5-trans-3-pyrroline products from starting materials with the appropriate aziridine geometry. Twenty three ring expansion examples, most of which feature a stereospecific cyclization, are presented.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6bb5e877a157304e0bd2b6b68e370ec1 https://doi.org/10.1002/chin.201123092 Zobrazit plný text záznamu Plný text