Discovery of the Potent and Selective MC4R Antagonist PF-07258669 for the Potential Treatment of Appetite Loss

Autor:	Michelle R. Garnsey, Aaron C. Smith, Jana Polivkova, Autumn L. Arons, Guoyun Bai, Caroline Blakemore, Markus Boehm, Leanne M. Buzon, Sarah N. Campion, Matthew Cerny, Shiao-Chi Chang, Karen Coffman, Kathleen A. Farley, Kari R. Fonseca, Kristen K. Ford, Jeonifer Garren, Jimmy X. Kong, Martin R. M. Koos, Daniel W. Kung, Yajing Lian, Monica M. Li, Qifang Li, Luis A. Martinez-Alsina, Rebecca O’Connor, Kevin Ogilvie, Kiyoyuki Omoto, Brian Raymer, Matthew R. Reese, Tim Ryder, Lacey Samp, Kimberly A. Stevens, Daniel W. Widlicka, Qingyi Yang, Kaicheng Zhu, Jean-Philippe Fortin, Matthew F. Sammons
Rok vydání:	2023
Předmět:	Drug Discovery Molecular Medicine
Zdroj:	Journal of Medicinal Chemistry. 66:3195-3211
ISSN:	1520-4804 0022-2623
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6ba50d658838cab5c2164045c8015f51 https://doi.org/10.1021/acs.jmedchem.2c02012 Zobrazit plný text záznamu