Abstract 99: Retrospective Analysis of Kawasaki Disease Patients Resistant to Second Intravenous Immunoglobulin

Autor: Minako Ono, Tomoyuki Miyamoto, Tetsuharu Nagamoto, Kataharu Sumi, Yoshinori Murashima, Ryusuke Sato, Ari Iwaoka, Yoko Santo, Yoko Mouri, Takeshi Mouri
Rok vydání: 2015
Předmět:
Zdroj: Circulation. 131
ISSN: 1524-4539
0009-7322
DOI: 10.1161/circ.131.suppl_2.99
Popis: Objective: This retrospective analysis aimed to identify the risk factors of Kawasaki disease (KD) resistant to second intravenous immunoglobulin ( IVIG) and design the score system discerning IVIG resistant patients in acute phase. Materials and Methods: A retrospective chart review of pediatric patients admitted to Children’s Medical Center, Yokosuka General Hospital Uwamachi with the diagnosis of KD during 2011 to 2013. In total 127 patients, 116 patients received IVIG and of 92 patients were respondent for initial course of IVIG. Rest of 17 patients received second course of IVIG and of 7 patients were resistant to second course of IVIG. Results: Logistic regression analysis showed that serum sodium concentration Conclusion: The score system based on easy and simple clinical factors might be useful for estimating the patients resistant to second IVIG and improve those patients’ further treatment.
Databáze: OpenAIRE