| Autor: |
Ashish Chintakuntlawar, Madhava Rao Kenja, Ashraf Alakkad, Aref Chehal |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Journal of Advances in Medicine and Medical Research. :316-321 |
| ISSN: |
2456-8899 |
| DOI: |
10.9734/jammr/2022/v34i224818 |
| Popis: |
This report describes a case of Vogt Koyanagi Harada Disease (VKH) in a 44-year-old male with metastatic gastric carcinoma who presented with sudden onset headache and decreased vision. The patient was treated with first-line standard therapy for stage IV HER2-positive gastric adenocarcinoma and was on maintenance trastuzumab and pembrolizumab for seven months before developing new symptoms. His VKH was diagnosed after multiple imaging and a comprehensive ophthalmologic examination. The patient’s vision and headaches improved with theinitiation of corticosteroid therapy. Although immunotherapy wasdiscontinued,trastuzumab was continuedwith close ophthalmology follow-up. He remains in stable conditiondespitehis cancer. It is critical to consider and recognize immunotherapy-relatedophthalmologic complications immediately, even if they are rare, considering theirimplications. Corticosteroids remain the first-line organ-saving therapy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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