Occupational radiation exposure and genetic polymorphisms in DNA repair genes
| Autor: | Farideh Zakeri, Mohammad Reza Rajabpour, Mohammad Reza Farshidpour |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Renewable Energy
Sustainability and the Environment DNA repair Health Toxicology and Mutagenesis Public Health Environmental and Occupational Health Biology 030218 nuclear medicine & medical imaging Toxicology 03 medical and health sciences 0302 clinical medicine Radiation sensitivity Nuclear Energy and Engineering XRCC3 MSH3 030220 oncology & carcinogenesis Immunology Genotype Micronucleus test Allele Safety Risk Reliability and Quality Waste Management and Disposal Gene |
| Zdroj: | Radioprotection. 52:241-249 |
| ISSN: | 1769-700X 0033-8451 |
| DOI: | 10.1051/radiopro/2017025 |
| Popis: | Radiation sensitivity appears to be influenced by genetic polymorphisms in some DNA repair genes and individuals with low DNA repair capacity can be at increased risk of developing cancer. The aim of the present study was to determine the impact of gene polymorphisms on DNA damages in the form of micronuclei (MN) in circulating lymphocytes of interventional cardiologists (ICs), occupationally exposed to ionizing radiation. MN frequency was significantly higher in the ICs than in the controls (27.7 ± 17.2‰ vs. 8.0 ± 2.6‰, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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