Luteinizing hormone receptor expression in leiomyomatosis peritonealis disseminata*1
| Autor: | Vasilios T. Goudas, Donald K. Brief, Ch.V. Rao, Dimitrios Danikas |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
medicine.medical_specialty
business.industry medicine.drug_class luteinizing hormone/choriogonadotropin receptor Mammary gland Obstetrics and Gynecology Ovary medicine.disease Menopause medicine.anatomical_structure Endocrinology Estrogen Internal medicine Medicine Gonadotropin business Luteinizing hormone Receptor hormones hormone substitutes and hormone antagonists |
| Zdroj: | Obstetrics & Gynecology. 95:1009-1011 |
| ISSN: | 0029-7844 |
| DOI: | 10.1016/s0029-7844(99)00587-6 |
| Popis: | Background: Leiomyomatosis peritonealis disseminata has been attributed to estrogen stimulation and is seen only rarely in postmenopausal women. In such cases, pathogenesis is uncertain. Case: Leiomyomatosis peritonealis disseminata tumors were resected from a postmenopausal woman. She was receiving tamoxifen therapy for breast cancer and had bilateral ovarian Brenner tumors. Estrogen and progesterone receptors were detected. Immunohistochemical analysis indicated that LH receptors were present. Conclusion: Luteinizing hormone receptors were identified in leiomyomatosis peritonealis disseminata in one woman. Levels of FSH and LH increase after menopause, and immunohistochemical analysis showed the presence of LH receptors, so gonadotropin rather than estrogen stimulation might have contributed to development of leiomyomatosis peritonealis disseminata in this uncommon case. |
| Databáze: | OpenAIRE |
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