Effects of Propofol Anaesthesia Pre-Medicated with Xylazine on Serum Biochemical Profiles and Sleep Pattern in Red Sokoto Goats

Autor: Abubakar Sadiq Yakubu, Adamu Abdul Abubakar, Ahmad I. Al-Mustapha, Saganuwan Alhaji Saganuwan
Rok vydání: 2020
Předmět:
Zdroj: International Journal of Veterinary Science.
ISSN: 2305-4360
2304-3075
Popis: This study was conducted with the objective to compare the sleep pattern and biochemical changes during general anesthesia at different timing interval with the baseline information using Propofol as the agent of choice and xylazine as a pre-medicant at 4 mg kg-1 intravenously and 0.025 mg kg-1 intramuscularly respectively. The onset of anaesthesia was rapid (30.1±11.3 seconds), the anaesthetic induction, surgical plane and recovery were good. There was a significant difference (P0.05) in pulse rate. Similarly, a statistically significant difference (P0.05) in the sodium ion, potassium ion, Alanine aminotransferase (ALT), Albumin (ALB), Aspartate aminotransferase (AST), , and Urea. It was concluded that the combination of Propofol and Xylazine at 4mgkg-1 and 0.25mgkg-1 respectively can be effectively and safely used for induction and maintenance of anaesthesia in Red Sokoto goats. It was also noted that recovery was smooth without any violence. The combination was also observed to have minimal effects on the clinico-biochemical parameters of Red Sokoto goats.
Databáze: OpenAIRE