Popis: |
We have performed more than 1500 “radioisotope arteriograms” by visualizing gamma emissions with a scintillation camera (Anger) during the first arterial circulation after the intravenous injection of a relatively non-diffusible radiopharmaceutical [2]. We believe that the technique is a rapid and efficient method for the identification of severe carotid artery stenosis and occlusion, middle cerebral artery occlusion, and arteriovenous malformation, and for post-operative evaluation of patients who have had carotid artery reconstructive surgery. It is an adjunct to rectilinear scanning that improves the probability of differentiating positive scans due to cerebral infarction, arteriovenous malformation and neoplasm. While the intravenous technique is useful for diagnosis, it cannot delineate quantitative variations in total or regional cerebral blood flow (rCBF). This report details our initial observations on the use of the scintillation camera and computer techniques to quantitate CBF. The techniques of radioisotope arteriography using Technetium-99m (99mTc), inhalation-recircu- lation, and arterial injection of Xenon-133 (133Xe) will be compared. |