| Popis: |
The most suitable drug delivery route is oral delivery due to its easily administration, patient adherence/ patient capacitance etc. Several approaches have been made for maximizing the G.R.T such as high-density system, floating system, swelling & expanding system and mucoadhesive & bio adhesive system etc. the main motive of reviewing the article is to focus on the mechanism of HBS system, classification with new system such as raft forming system and hollow microsphere, its application, marketed preparation and evaluation study. The procedure of gastric emptying is a complex and may leads to uncertainty for in vivo performance of the DDS. To prevent this type of complex formation and uncertainty, hard work has been done to expand the retention time of DDS for half of the day. The FDDS are beneficial in such process. Keywords: HBS system, GRDDS, gastric residence time (G.R.T), raft forming systems, floating formulations, evaluation study. |
