Hydration of Glucose and Galactose Derivatives

Autor:	Sakae Tsuda, Hisashi Uedaira, Hatsuho Uedaira, Shoichi Okouchi
Rok vydání:	2001
Předmět:	chemistry.chemical_compound Aqueous solution chemistry Glucosamine Coordination number Galactose Relaxation (NMR) Molecule Organic chemistry General Chemistry Medicinal chemistry
Zdroj:	Bulletin of the Chemical Society of Japan. 74:1857-1861
ISSN:	1348-0634 0009-2673
DOI:	10.1246/bcsj.74.1857
Popis:	The spin-lattice relaxation times, T1, of H217O have been measured for aqueous solutions of glucose and galactose derivatives, which are substituents of the 2-OH or 6-OH of these sugars, as a function of the concentration at 25 °C. The values of the coordination numbers, nh, have been estimated on the basis of the water-accessible surface areas (ASA) of the solute molecules. The rotational correlation times, τch, of water molecules around the solute were estimated and compared with that of pure water, τc0. All values of the τch/τc0 for the derivatives were smaller than those of the parent sugars, and the value of τch/τc0 = 1.26 for glucosamine was the smallest among these derivatives. The greater the hydration of the parent sugars is, the more the hydration layer will be disturbed by the substituted groups.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6b4fe30f946f363abff012b38fe3e161 https://doi.org/10.1246/bcsj.74.1857 Zobrazit plný text záznamu