Growth Hormone (GH) Releasing Hormone- and Thyrotropin Releasing Hormone-Induced GH Release in the Acute Phase of Trauma

Autor: Francesco Della Corte, Domenico Valle, Edoardo Menini, Gianluigi Conte, Vittorio Mignani, Antonio Mancini, M. Perrelli, Laura De Marinis, Paolo Carducci
Rok vydání: 1996
Předmět:
Zdroj: Growth Hormone Secretagogues ISBN: 9781461275268
DOI: 10.1007/978-1-4612-2396-2_21
Popis: A great number of metabolic and hormonal derangements have been described in traumatized patients. Plasma concentrations of many substrates, enzymes, and metabolites rise and/or fall, and indices of organ and tissue function change without unequivocal overall patterns. Endocrine variations can mediate a lot of these metabolic pathway dysfunctions; in general two different secretory patterns can be seen in anterior pituitary hormones: an increase of adrenocorticotropic hormone (ACTH), prolactin (PRL), and growth hormone (GH) and a decrease of other hormones [thyroid stimulating hormone (TSH), luteinizing hormone (LH), follicle stimulating hormone (FSH)]. Neurohypophysial hormones can be involved depending on the kind of trauma. Catecholamines, insulin, and glucagon levels also change, and are of fundamental importance in the regulation of intermediate metabolism in such patients.
Databáze: OpenAIRE