Iontophoretic transport of associates based on porous Keplerate-type cluster polyoxometalate Mo72Fe30 and containing biologically active substances

Autor: Irina G. Danilova, A. A. Ostroushko, I. D. Gagarin, M. O. Tonkushina, I. F. Gette, Grigoriy Kim, K. V. Grzhegorzhevskii
Rok vydání: 2017
Předmět:
Zdroj: Russian Journal of Physical Chemistry A. 91:1811-1815
ISSN: 1531-863X
0036-0244
DOI: 10.1134/s0036024417090230
Popis: The possibility of iontophoretic transport through the native membranes of biologically active substances (vitamin B1 and insulin) associated with porous clusters Mo72Fe30 polyoxometalate of the Keplerate type is demonstrated for the first time in an experimental setup. The diffusion coefficient is estimated. The possibility of transferring Keplerate ions with a protective coating of biocompatible polymer polyvinylpyrrolidone is also shown.
Databáze: OpenAIRE