Electrochemically enabled rhodium-catalyzed [4 + 2] annulations of arenes with alkynes

Autor:	Shao-Fei Ni, Qiang Ma, Li-Rong Wen, Ming Li, Lin-Bao Zhang, Jia-Yi Chen, Rui-Tao Li, Zi-Chen Wang
Rok vydání:	2021
Předmět:	Electrolysis Aqueous solution Regioselectivity chemistry.chemical_element Pollution Combinatorial chemistry law.invention Catalysis Rhodium chemistry.chemical_compound chemistry law Functional group Environmental Chemistry Stoichiometry
Zdroj:	Green Chemistry. 23:9515-9522
ISSN:	1463-9270 1463-9262
DOI:	10.1039/d1gc03187b
Popis:	Herein, electrochemically driven, Rh(III)-catalyzed regioselective annulations of arenes with alkynes have been established. The strategy, combining the use of a rhodium catalyst with electricity, not only avoids the need for using a stoichiometric amount of external oxidant, but also ensures that the transformations proceed under mild and green conditions, which enable broad functional group compatibility with a variety of substrates, including drugs and pharmaceutical motifs. Moreover, the electrolysis reaction was made operationally simple by employing an undivided cell, and proceeds efficiently in aqueous solution in air.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6b425302ff99272f01e901207ff32507 https://doi.org/10.1039/d1gc03187b Zobrazit plný text záznamu