Effect of a Cosmetic Use with 2% Isostearyl-L-Ascorbic Acid Gel for Postinflammatory Hyperpigmentation and Postinflammatory Erythema in Acne Vulgaris
| Autor: | Ichiro Kurokawa, Masako Watanabe, Kazuhito Hayashibe |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0303 health sciences
medicine.medical_specialty Erythema business.industry medicine.disease Ascorbic acid Dermatology 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine embryonic structures medicine medicine.symptom business Acne Postinflammatory hyperpigmentation 030304 developmental biology |
| Zdroj: | Journal of Cosmetics, Dermatological Sciences and Applications. 10:28-32 |
| ISSN: | 2161-4512 2161-4105 |
| Popis: | Postinflammatory hyperpigmentation (PIH) and postinflammatory erythema (PIE) in acne vulgaris are important and refractory complications for patients with acne vulgaris. To clarify the effects of 2% isostearyl-L-ascorbic acid (ISAA) against PIH and PIE in acne vulgaris, a clinical pilot study with topical 2% ISAA gel was performed in 25 acne patients with PIH and PIE. Topical ISAA gel was applied on the whole face with PIH and PIE in acne vulgaris twice a day for 3 months. Regarding PIH and PIE, investigator’s global improvement rating (IGIR) was evaluated in 7-point scales according to the reduced area of PIH and PIE before and after the study. Remarkable improvement in PIH was observed in 7 patients (28.0%) and in PIE in 12 (48%) of the 25 patients. No adverse reactions were observed during the treatment. Topical ISAA application can be an alternative, non-invasive available treatment for PIH and PIE in acne vulgaris. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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