Functionalization and Magnetic Relaxation of Ferrite Nanoparticles for Theranostics
| Autor: | Yuko Ichiyanagi, Tatsuya Hashimoto, Takahiro Yamazaki, Yoshiyuki Hosokai, Haruo Saito, Taisei Ide, Tomoya Ishikawa, Akito Oshima, K. Miike, Koki Fujiwara, Daiki Shigeoka, Akihito Usui, Kouhei Kanda, Daiki Aihara |
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| Rok vydání: | 2018 |
| Předmět: |
010302 applied physics
Materials science Hyperthermia Treatment Nanoparticle 02 engineering and technology 021001 nanoscience & nanotechnology 01 natural sciences Magnetic susceptibility Electronic Optical and Magnetic Materials Amorphous solid Nuclear magnetic resonance 0103 physical sciences Surface modification Ferrite (magnet) Magnetic nanoparticles Electrical and Electronic Engineering 0210 nano-technology Nanoscopic scale |
| Zdroj: | IEEE Transactions on Magnetics. 54:1-7 |
| ISSN: | 1941-0069 0018-9464 |
| DOI: | 10.1109/tmag.2018.2845132 |
| Popis: | Magnetic nanoparticles have drawn attention recently due to their interesting nanoscopic features and potential applications. Various kinds of ferrite nanoparticles with diameters between 3 and 34 nm encapsulated by amorphous SiO2 were functionalized and examined for biomedical applications. From dc and ac magnetic susceptibility measurements, it was found that these particles followed the Neel relaxation system. Co–Zn ferrite (Co0.8Zn0.2Fe2O4) nanoparticles were prepared and the increase in temperature in the ac field was estimated for hyperthermia treatment. In vitro experiments using cultured human breast cancer cells were carried out, and a dramatic hyperthermia effect was observed. As one of the diagnostic methods, magnetic resonance (MR) measurements were performed for CoFe2O4 nanoparticles, and the samples were also evaluated as potential contrast media for MR imaging. |
| Databáze: | OpenAIRE |
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