Models and methods for evaluating geroprotective activity of pharmacological drugs
Autor: | Vladimir N. Anisimov, M. A. Zabezhinski, Irina G. Popovich |
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Rok vydání: | 2011 |
Předmět: | |
Zdroj: | Advances in Gerontology. 1:81-94 |
ISSN: | 2079-0589 2079-0570 |
Popis: | We reviewed current approaches to evaluating the efficacy and safety of potential lifespan-extending drugs (geroprotectors). We described and approved our own protocol for evaluation of geroprotectors in mice. Principles and criteria for assessing the gist of the argument of the geroprotective properties of pharmacological drugs in experiments with animals and humans are discussed. |
Databáze: | OpenAIRE |
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