Additional file 4: Figure S4. of Zbtb20 modulates the sequential generation of neuronal layers in developing cortex

Autor: Tonchev, Anton, Tuoc, Tran, Rosenthal, Eva, Studer, Michèle, Stoykova, Anastassia
Rok vydání: 2016
DOI: 10.6084/m9.figshare.c.3620591_d3
Popis: Enhanced presence of lower layer neurons in primary motor cortex of Zbtb20 lacZ/lacZ mutants. (A1-A2) NeuN IHC demonstrating an overview of the motor cortex (depicted on the scheme in the upper left corner) on cross brain sections. The enlargement of L6 and L5 and the thinning of L2-L4 is apparent. (B1-B3) Decreased numbers of L2-L4 Cux1-immunostained neurons in Zbtb20-deficient cortex. (C1-D3) Immunostaining with FoxP1 (C1,C2) and Ctip2 (D1,D2) antibodies revealed in the Zbtb20 mutant an increased number of both FoxP2+ L6 and Ctip2+ L5 neurons. (B3,C3,D3) Graphs representing statistical evaluation of the results (*, P
Databáze: OpenAIRE