Multiple Antiviral Activities of Endemic Medicinal Plants Used by Berber Peoples of Morocco
| Autor: | G.H.N. Towers, M. Rejdali, James B. Hudson, F. Mouhajir |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Pharmacology
Sindbis virus biology Traditional medicine Rosa canina viruses Pharmaceutical Science General Medicine biology.organism_classification medicine.disease_cause Virus Lawsonia inermis Herpes simplex virus Complementary and alternative medicine Punica Drug Discovery medicine Molecular Medicine Enterovirus Medicinal plants |
| Zdroj: | Pharmaceutical Biology. 39:364-374 |
| ISSN: | 1744-5116 1388-0209 |
| DOI: | 10.1076/phbi.39.5.364.5892 |
| Popis: | We investigated the antiviral activities of methanol extracts of 75 Moroccan plants (64 genera of 35 families), used traditionally to treat diseases that could be caused by viruses and microbes. The plants included many endemic to Morocco and used by Berber as well as Arab peoples. They were evaluated against three mammalian viruses: herpes simplex virus, Sindbis virus and poliovirus, at non-cytotoxic concentrations. Five extracts were very active against the three viruses, 16 were active against two viruses, and 24 were only active against one virus. Thirty-two extracts showed light enhanced and two showed light-dependent activities. Punica granatum extract, which was the most active, inhibited all three viruses at a concentration of only 1.5 µg/ml, although these activities were not light enhanced. The extracts of Acacia gummifera, Juglans regia, Thymus maroccanus, Lawsonia inermis, Pinus halepensis, and Rosa canina inhibited Sindbis virus at a minimum concentration of 1.5 µg/ml. Thymus maroccanus and R... |
| Databáze: | OpenAIRE |
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