Regulation of Inhibin and Activin Genes in the Rat Ovary

Autor: Joanna C. Dykema, Jason O. Rahal, Kelly E. Mayo
Rok vydání: 1991
Předmět:
Zdroj: Signaling Mechanisms and Gene Expression in the Ovary ISBN: 9781461278306
DOI: 10.1007/978-1-4612-3200-1_8
Popis: The gonadotropins, luteinizing hormone (LH) and follicle stimulating hormone (FSH), play major roles in regulating the mammalian reproductive cycle by influencing the gametogenic and steroidogenic functions of the gonads (1, 2). The simultaneous release of LH and FSH from anterior pituitary gonadotrophs is known to be positively regulated by the hypothalamic decapeptide GnRH (3,4). More recently, several gonadal peptides that specifically modulate FSH synthesis and secretion have been isolated and characterized. These include the inhibins, activins, and follistatin (5-12).
Databáze: OpenAIRE