The Synthesis of a Combretastatin A-4 Based Library and Discovery of New Cooperative ortho-Effects in Wittig Reactions Leading to (Z)-Stilbenes

Autor:	David C. Harrowven, Melanie Howell, Ian L. Guy, Graham Packham
Rok vydání:	2006
Předmět:	Combretastatin Combretastatin A-4 chemistry.chemical_compound chemistry Yield (chemistry) Organic Chemistry Wittig reaction Total synthesis Combinatorial chemistry
Zdroj:	Synlett. 2006:2977-2980
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-2006-948200
Popis:	A synthesis of combretastatin A-4 and a small library of analogues led to the discovery of some new cooperative ortho-­effects allowing (Z)-stilbenes to be prepared in high yield and dia­stereomeric ratio.
Databáze:	OpenAIRE
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