The Controlled Release of 5-Fluorouracil from Acrylate Copolymers of 1-(N-2-Ethylmethacrylcarbamoyl)-5-Fluorouracil Monomer

Autor:	Charles G. Gebelein, Robert R. Hartsough
Rok vydání:	1985
Předmět:	chemistry.chemical_compound Acrylate Monomer chemistry Polymerization Butyl acrylate Polymer chemistry technology industry and agriculture Copolymer macromolecular substances Methacrylate Methyl acrylate Controlled release
Zdroj:	Polymeric Materials in Medication ISBN: 9781489922472
DOI:	10.1007/978-1-4899-2245-8_10
Popis:	The preparation, polymerization and copolymerization of a novel methacrylate type monomer containing 5-fluorouracil is described. The methyl and butyl acrylate copolymers show zero order release behavior, and can deliver a constant level of 5-fluorouracil for time periods greater than 240 hours. These zero order release profiles were obtained without any special membranes or device designs, and were characteristic of the polymeric material itself.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6ac5f0850d721e69e8c916ea99926fff https://doi.org/10.1007/978-1-4899-2245-8_10 Zobrazit plný text záznamu