Granular cell cutaneous epithelioid angiomatous nodule
Autor: | Timothy C Sorrells, Aubrey E Winn, Daryl J Sulit |
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Rok vydání: | 2019 |
Předmět: |
CD31
Pathology medicine.medical_specialty Histology Chemistry Cell Nodule (medicine) Dermatology Pathology and Forensic Medicine 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure Granular cell Cytoplasm 030220 oncology & carcinogenesis Eosinophilic medicine Angiosarcoma medicine.symptom Erg |
Zdroj: | Journal of Cutaneous Pathology. 46:864-866 |
ISSN: | 1600-0560 0303-6987 |
Popis: | Cutaneous epithelioid angiomatous nodule is an uncommon vascular lesion usually described as composed of epithelioid endothelial cells with vesicular nuclei and eosinophilic cytoplasm. A granular cell variant has not been previously described. Endothelial cells can present with granular cytoplasm as documented with reports of granular cell angiosarcoma. The granularity is thought to be due to increased intracytoplasmic lysosomes. We present a case of a benign superficial vascular lesion composed of a sheet-like proliferation of epithelioid endothelial cells with distinctly granular cytoplasm confirmed as of endothelial origin with positive staining for CD31 and ERG. |
Databáze: | OpenAIRE |
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