Primärer Hyperreninismus: Eine seltene Ursache der sekundären arteriellen Hypertonie

Autor:	J. M. Gasc, F. J. Kessler, R. Kreutz, U. Pfeifer, D. Ganten, H. Zhou
Rok vydání:	2008
Předmět:	medicine.medical_specialty Kidney medicine.diagnostic_test business.industry medicine.medical_treatment Urology Diastole General Medicine Scintigraphy Nephrectomy medicine.anatomical_structure Blood pressure Laparotomy Renin–angiotensin system medicine Immunohistochemistry business
Zdroj:	DMW - Deutsche Medizinische Wochenschrift. 118:1110-1114
ISSN:	1439-4413 0012-0472
Popis:	In 1975, scintigraphy revealed a 6.5 x 5 cm tumour in the region of the left adrenal in a 36-year-old man with known hypertension for 5 years (systolic pressure up to 250 mm Hg, diastolic up to 130 mm Hg). A laparotomy was performed for a suspected phaeochromocytoma. A tumour was located in the upper pole of the kidney and removed together with the kidney. The blood pressure quickly returned to normal after the operation: it remained stable for the following 17 years (between 130/80 to 150/90 mm Hg). Originally the tumour could not be clearly classified either clinically or histologically. But recently the paraffin-imbedded tumour specimen was re-examined by immunohistochemistry and in-situ hybridization. This identified a renin-producing tumour so that primary reninism was the cause of the arterial hypertension.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6ab191548b7e2220cf84408304342b13 https://doi.org/10.1055/s-2008-1059433 Zobrazit plný text záznamu