Conjugated polymer-hybridized silica nanoparticle as a fluorescent sensor for cysteine
| Autor: | Geunseok Jang, Taek Seung Lee |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
chemistry.chemical_classification
Materials science Polymers and Plastics 02 engineering and technology General Chemistry Polymer Conjugated system 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics Photochemistry 01 natural sciences Combinatorial chemistry Fluorescence Aldehyde 0104 chemical sciences Amino acid Suzuki reaction chemistry Polymerization Materials Chemistry 0210 nano-technology Cysteine |
| Zdroj: | Polymer Bulletin. 73:2447-2456 |
| ISSN: | 1436-2449 0170-0839 |
| DOI: | 10.1007/s00289-016-1672-9 |
| Popis: | The detection of important biological thiols such as cysteine (Cys) is highly relevant to a variety of fundamental physiological processes in organisms. A conjugated polymer with pendant aldehyde group, which was used for reactive site for Cys, was synthesized via Suzuki coupling polymerization and the polymer was immobilized on the surface of amine-functionalized silica nanoparticles. The conjugated polymer-modified silica nanoparticles could be dispersed in alcoholic media, exhibiting various emission colors according to the alcoholic media, presumably due to the various polarity of the alcohols used. The organic–inorganic hybrid showed changes in emission color upon exposure to Cys with high selectivity over other amino acids, because of the specific reaction of aldehyde in the polymer and aminothiol group in Cys. |
| Databáze: | OpenAIRE |
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