Acyclovir Neurotoxicity and Nephrotoxicity-The Role for Hemodialysis

Autor: Melvin R. Glick, Michael D. Clayman, Barry F. Krieble, David W. Rudy
Rok vydání: 1993
Předmět:
Zdroj: The American Journal of the Medical Sciences. 305:36-39
ISSN: 0002-9629
Popis: Severe neurotoxicity and acute renal failure developed in a patient with newly diagnosed AIDS while receiving high-dosage intravenous acyclovir for disseminated herpes zoster. Hemodialysis resulted in a rapid resolution of neurologic symptoms and was associated with a reduction in plasma acyclovir concentration. Acute hemodialysis therapy should be considered in cases of serious neurotoxicity secondary to acyclovir, especially when accompanied by renal failure.
Databáze: OpenAIRE