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| Autor: | Christian D Mallen, Charles A. Hay, John Belcher, Edward Roddy, James A. Prior |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
musculoskeletal diseases
congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty integumentary system business.industry nutritional and metabolic diseases Allopurinol hypersensitivity syndrome Allopurinol medicine.disease Dermatology Gout Rheumatology medicine heterocyclic compounds In patient South east asian business medicine.drug |
| Zdroj: | Arthritis Care & Research. 74:161-162 |
| ISSN: | 2151-4658 2151-464X |
| DOI: | 10.1002/acr.24777 |
| Popis: | We thank Dr Lai for their interest in our study (1). While we did not show a statistically significant link between the use of allopurinol and mortality in people with gout, we agree that Allopurinol Hypersensitivity Syndrome (AHS) is the most serious side-effect of allopurinol, particularly in populations with South East Asian ancestry, leading to the recommendation to screen people of South East Asian descent for the HLA-B*5801 allele prior to starting treatment with allopurinol (2,3). |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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