Palladium catalysed asymmetric alkylation of benzophenone Schiff base glycine esters in ionic liquids

Autor:	Hoon Sik Kim, Dae Won Kim, Deb Kumar Mukherjee, Jin Kyu Im, Minserk Cheong, Dae Hyun Kim
Rok vydání:	2011
Předmět:	Schiff base Enantioselective synthesis chemistry.chemical_element General Chemistry Alkylation Catalysis chemistry.chemical_compound chemistry Ionic liquid Polymer chemistry Benzophenone Organic chemistry Enantiomeric excess Palladium
Zdroj:	Journal of Chemical Sciences. 123:467-476
ISSN:	0973-7103 0974-3626
DOI:	10.1007/s12039-011-0093-4
Popis:	Asymmetric alkyl substitution of various benzophenone Schiff base substrates under biphasic conditions proceeded using optically active Palladium(II) complexes. The corresponding products were obtained in high yields but with moderate enantiomeric excess (ee). Addition of specific ionic liquids to the reaction medium enhanced reactivity and selectivity for phase transfer catalytic (PTC) glycine alkylation. It has been found that there is an anionic influence of the ionic liquids that modify the steric environment around the enolate ion. A computer-assisted molecular design of enantioselective phase-transfer catalysis with the palladium complex and the ionic liquid has been done.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6a8a413ab7bb52c757ed4a44ae9bf2c2 https://doi.org/10.1007/s12039-011-0093-4 Zobrazit plný text záznamu Plný text ve formátu PDF