Collagenous colitis: Clinical and histological spectrum in ten patients

Autor:	Charles Steadman, Owen Harris, Paul Kerlin, Kevin J Hourigan, John Sampson, Clinton Teague
Rok vydání:	1987
Předmět:	medicine.medical_specialty Pathology Hepatology Collagenous colitis Erythema business.industry Rectal biopsy Gastroenterology medicine.disease Colonic mucosa Pharmacotherapy Internal medicine Watery diarrhoea Medicine Colitis medicine.symptom business
Zdroj:	Journal of Gastroenterology and Hepatology. 2:459-466
ISSN:	1440-1746 0815-9319
DOI:	10.1111/j.1440-1746.1987.tb00190.x
Popis:	Collagenous colitis is characterized by the presence of a thick subepithelial collagen band in the colonic mucosa. The condition was diagnosed on rectal biopsy in 10 patients (one male, nine females) who presented with watery diarrhoea. Although rectal mucosal erythema was present in three and ulceration in two, the mucosa was of normal endoscopic appearance in five of the patients. There was marked variability in the thickness of the submucosal collagen band, both between and within individuals. Empirical drug therapy included sulphasalazine, glucocorticoids and antidiarrhoeals. All patients reported symptomatic improvement.
Databáze:	OpenAIRE
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