Lipophilic hexadentate gallium, indium and iron complexes of new phenolate-derivatized cyclohexanetriamines as potential in vivo metal-transfer reagents
| Autor: | Joel T. Mague, William A. Banks, D. Max Roundhill, Charles J. O′Connor, James E. Bollinger |
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| Rok vydání: | 1995 |
| Předmět: | |
| Zdroj: | J. Chem. Soc., Dalton Trans.. :1677-1688 |
| ISSN: | 1364-5447 0300-9246 |
| DOI: | 10.1039/dt9950001677 |
| Popis: | 1,3,5-Tris(5-substituted salicylamino)cyclohexanes (H3L; R = H, NO2 or OMe) have been synthesized by Schiff-base condensation between cis-1,3,5-triaminocyclohexane and a substituted salicylaldehyde, followed by reduction with KBH4. Reaction of these compounds with gallium(III), indium(III) and iron(III) salts gave neutral six-co-ordinate N3O3 complexes of type [ML](M = Ga, In or Fe). The complexes have been characterized by a combination of infrared, 1H and 13C-{1H} NMR and mass spectroscopy. The distribution coefficients between octan-1-ol and water indicate that the complexes are lipophilic. The electronic absorption spectra of the high-spin iron(III) complexes show ligand-to-metal charge-transfer bands in the 450–500 nm range. The structures of five of the complexes have been confirmed by single-crystal X-ray crystallography. |
| Databáze: | OpenAIRE |
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