Association of polymorphism in the serotonin transporter gene promote with the susceptibility to alcohol dependence in Yunnan Han Population

Autor:	Wang Xj, Jing Q, Bao Jj, Zhong, Wu Wy, Dou Sj
Rok vydání:	2011
Předmět:	Genetics Alcohol dependence Alcohol Promoter General Medicine Biology Genotype frequency chemistry.chemical_compound chemistry Polymorphism (computer science) Genotype biology.protein Allele Serotonin transporter
Zdroj:	Hereditas (Beijing). 33:48-53
ISSN:	0253-9772
DOI:	10.3724/sp.j.1005.2011.00048
Popis:	To explore the association of polymorphism in the serotonin transporter gene and the susceptibility to alcohol dependence in Yunnan Han population, PCR and DNA sequencing techniques were used to detect 5-HTT-linked promoter region (5-HTTLPR). One hundred and eighteen alcohol dependent patients as case group and 214 normal people as control group were employed in this study. Significant differences in genotype frequencies were present between case group and control group of 5-HTTLPR (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6a3fa3d4e97bf3a435e8db883903c3da https://doi.org/10.3724/sp.j.1005.2011.00048 Zobrazit plný text záznamu