Effects of caudate stimulation on visual discrimination

Autor: E.J. Wyers, J. Carlin, R.E. Farley, N.A. Buchwald
Rok vydání: 1961
Předmět:
Zdroj: Experimental Neurology. 4:23-36
ISSN: 0014-4886
Popis: Bilateral stimulation of the head of the caudate nucleus in cats has two separable effects upon the performance of a visual discrimination. The first is a reduction in accuracy in a task which has not been completely learned. The same stimulation has no effect in an “overtrained” task. The second effect is an increase in reaction time. This occurs regardless of accuracy. The increase in reaction time is a “inertial” effect, that is, the animal performs smoothly and rapidly when he makes his response, but shows difficulty in initiating it. Parameters of stimulation of the caudate nucleus which produce these effects are 5-per-second bilateral pulses delivered for 3 sec at an intensity sufficient to produce “caudate spindles” in the alert animal. Stimuli below this intensity fail to effect accuracy or reaction time. The results are discussed in terms of an inhibitory feedback circuit which involves the thalamus and the caudate nucleus.
Databáze: OpenAIRE