Effects of an equol-producing bacterium isolated from human faeces on isoflavone and lignan metabolism in mice

Autor: Takuya Sugahara, Hiroyuki Nakagawa, Satoshi Yamauchi, Sachiko Hori, Motoi Tamura
Rok vydání: 2015
Předmět:
Zdroj: Journal of the Science of Food and Agriculture. 96:3126-3132
ISSN: 0022-5142
Popis: BACKGROUND Equol is a metabolite of daidzein that is produced by intestinal microbiota. The oestrogenic activity of equol is stronger than daidzein. Equol-producing bacteria are believed to play an important role in the gut. The rod-shaped and Gram-positive anaerobic equol-producing intestinal bacterium Slackia TM-30 was isolated from healthy human faeces and its effects on urinary phyto-oestrogen, plasma and faecal lipids were assessed in adult mice. RESULTS The urinary amounts of equol in urine were significantly higher in mice receiving the equol-producing bacterium TM-30 (BAC) group than in the control (CO) group (P
Databáze: OpenAIRE