| Autor: |
J. R. De Souza, Haiana Charifker Schindler, Marta Maciel Lyra Cabral, Daniele Silva de Moraes Van-Lume, Valdir de Queiroz Balbino, Silvia Maria Lucena Montenegro, Frederico G. C. Abath, M. H. Saad, J. C. Rego |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Scandinavian Journal of Immunology. 72:460-468 |
| ISSN: |
0300-9475 |
| DOI: |
10.1111/j.1365-3083.2010.02459.x |
| Popis: |
Diagnostic tests for tuberculosis (TB) using interferon gamma (IFN-γ) responses produced by T lymphocytes after stimulation by early secretory antigen target 6 (ESAT-6), culture filtrate protein 10 (CFP-10) or purified protein derivate (PPD) were carried out using ELISA (enzyme-linked immunosorbent assay) in whole blood culture supernatants from children with suspected TB disease (n=21), latent TB infection (LTBI; n=17) and negative controls (NC; n=21) from Recife, Pernambuco, Brazil. The results were analysed using the ROC (receiver operating characteristic) curves and the areas under the curve (AUC) generated varied from 0.5 to 1.0 with higher values indicating increased discriminatory ability. Comparisons of AUCs were made using non-parametric assumptions, and the differences were considered significant if P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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