Gender-specific analysis of outcomes from endoscopic sinus surgery for chronic rhinosinusitis

Autor:	Rohit Divekar, Zachary A. Elwell, Yu Hui Chang, Devyani Lal, Kimberly B. Golisch, Matthew A. Rank
Rok vydání:	2016
Předmět:	medicine.medical_specialty medicine.diagnostic_test Chronic rhinosinusitis business.industry medicine.disease Surgery Endoscopy 03 medical and health sciences Endoscopic sinus surgery 0302 clinical medicine Otorhinolaryngology Symptom relief 030220 oncology & carcinogenesis medicine Immunology and Allergy Anxiety Nasal polyps medicine.symptom 030223 otorhinolaryngology Sinusitis business Depression (differential diagnoses)
Zdroj:	International Forum of Allergy & Rhinology. 6:896-905
ISSN:	2042-6976
DOI:	10.1002/alr.21773
Popis:	Background Women electing endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS) report higher symptom burden but have lower computed tomography (CT) scores. Gender-specific analysis of outcomes from ESS therefore merits further study. The objective of this work was to study gender-specific differences in outcomes from ESS for CRS by analyzing preoperative and postoperative 22-item Sino-Nasal Outcome Test (SNOT-22) scores. Methods Data from adult CRS patients electing ESS (2011-2013) were retrospectively collected. SNOT-22 total, rhinologic/nonrhinologic subdomain, and individual item scores were analyzed for gender-specific differences. Results Two hundred and forty-eight patients met study criteria (mean age 55.4 years; 49.6% female). Preoperatively, mean Lund-Mackay CT score was 11.1; average total SNOT-22 score was 41.9. Compared to men, women had lower CT score (10.2 vs 12.0; p = 0.004) but higher total SNOT-22 score (44.7 vs 39.1; p = 0.02). Both genders showed significant improvement in total SNOT-22 scores at 3, 6, 12, and 24 months following ESS (p < 0.001), with largely similar slopes of improvement. The greatest improvement occurred at 3 months (SNOT-22 decreased by 25.4 points), with stable improvement after 12 months (SNOT-22 decreased by 21.3 points). Higher total SNOT-22 scores in females were noted preoperatively and until 6 months post-ESS; these were driven by rhinologic and nonrhinologic-otolaryngic subdomain items. No gender differences in anxiety/depression prevalence or psychological subdomain scores were noted preoperatively or postoperatively. Conclusion Both male and female CRS patients showed significant and durable symptom relief following ESS. Women reported higher symptom burden prior to surgery, and in the early postoperative period. However, after 1-year post-ESS, both genders showed similar symptom scores. The trend and magnitude of improvement were similar in both genders.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6a0d5eb20c489f31cc9bf02f0172c2fb https://doi.org/10.1002/alr.21773 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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