The hydrostannation of a propargylglycine derivative
| Autor: | Markus G. Gebauer, Geoffrey T. Crisp |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
chemistry.chemical_classification
Chemistry Allylglycine Organic Chemistry Regioselectivity Alkyne chemistry.chemical_element Tributyltin hydride Biochemistry Catalysis Inorganic Chemistry chemistry.chemical_compound Transition metal Materials Chemistry Organic chemistry Physical and Theoretical Chemistry Tin |
| Zdroj: | Journal of Organometallic Chemistry. 532:83-88 |
| ISSN: | 0022-328X |
| Popis: | The hydrostannation of methyl ( R,S )-2-( N -diphenylmethylidene) aminopent-4-ynoate induced by a wide variety of transition metal complexes has been studied. The resulting isomeric α-amino acid derivatives featured a tributylvinylstannane in the side-chain and were separated by chromatography. A total of 24 different conditions were screened for this reaction in an attempt to effect a regioselective addition of tributyltin hydride to the alkyne group Regioisomeric mixtures were formed in all cases and for some catalysts reduction to the allylglycine derivative was also significant. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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