Histomorphological Study of the Anti-Fertility Effect of Spondias Mombin L. In Adult Male Rats

Autor:	Mokutima A. Eluwa, O. R. Asuquo, P. B. Udoh, Theresa B. Ekanem
Rok vydání:	2012
Předmět:	Germinal epithelium Infertility medicine.medical_specialty biology food and beverages biology.organism_classification medicine.disease Sertoli cell Epididymis Sperm Endocrinology medicine.anatomical_structure Internal medicine medicine Spermatogenesis Testosterone Spondias mombin
Zdroj:	IOSR Journal of Pharmacy and Biological Sciences. 3:29-34
ISSN:	2278-3008 2319-7676
DOI:	10.9790/3008-0322934
Popis:	The effects of ethanol extract of Spondias mombin leaf on male rats' fertility were investigated. The extract was orally administered with 250 and 500mg/kg doses for 8 weeks. There was significant decrease in testicular and epididymal weight in the treated animals compared to the control. Histomorphology of the testis showed distortion in the arrangement of seminiferous tubules, loose germinal epithelium, low number of germ cells and Sertoli cells. Tubular sizes of epididymis were reduced with vacuolation and decreased sperm. The serum level of testosterone was significantly decreased (p
Databáze:	OpenAIRE
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