Thrombotic Thrombocytopenic Purpura Induced by Trimethoprim-Sulfamethoxazole in a Patient with Rheumatoid Arthritis
| Autor: | Wan-Hee Yoo, Ji Youn Sohn, Kyung Ae Lee, Yun Kyung Hong |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
medicine.medical_specialty
business.industry Sulfamethoxazole Thrombotic thrombocytopenic purpura Microangiopathic hemolytic anemia respiratory system bacterial infections and mycoses medicine.disease Trimethoprim Gastroenterology Thrombocytopenic purpura Psychiatry and Mental health Neuropsychology and Physiological Psychology Glucocorticoid therapy hemic and lymphatic diseases Internal medicine Rheumatoid arthritis Immunology medicine heterocyclic compounds Therapeutic plasma exchange business therapeutics medicine.drug |
| Zdroj: | The Journal of the Korean Rheumatism Association. 16:296 |
| ISSN: | 1226-8070 |
| DOI: | 10.4078/jkra.2009.16.4.296 |
| Popis: | Thromobotic thrombocytopenic purpura (TTP) is a multisystem disorder that’s characterized by consumptive thrombocytopenia, microangiopathic hemolytic anemia,and neurologic symptoms. TTP is associated with many diseases and several therapeutic drugs. We report here on the first Korean case of a patient with rheumatoid arthritis (RA) and who developed TTP that was associated with trimethoprim-sulfamethoxazole (TMP-SMX) in Korea. She recovered from the TTP following daily sessions of therapeutic plasma exchange (TPE) with fresh plasma replacement and glucocorticoid therapy. Awareness of the possible development of TTP in patient with RA and who is being treated with TMP-SMX is important for making the early diagnosis and administering proper treatment. |
| Databáze: | OpenAIRE |
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