HIV Antibodies Screening in At-Risk Groups in Yaound� (Cameroon)
| Autor: | L. Zekeng, G. Garrigue, M. Lando, A. Mbakop, J. P. Durand, M. Monny-Lobe, L. Kaptue-Noche, M. Ossondo-Nlom |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Pregnancy education.field_of_study Blood transfusion Obstetrics business.industry Transmission (medicine) medicine.medical_treatment Population Disease medicine.disease Serology Acquired immunodeficiency syndrome (AIDS) Immunology medicine Seroprevalence business education |
| DOI: | 10.1159/000415523 |
| Popis: | In an effort to prevent the transmission of human immunodeficiency virus (HIV) through blood transfusion all blood donors in Yaounde Cameroon are systematically screened. Of the 3535 donors screened between February-September 1987 only 10 (0.28%) were positive for HIV infection. Serologic tests were also performed on other population groups with the following rates of HIV seropositivity: 483 blood transfusion recipients (the majority with sickle cell disease) 0.4%; 30 patients with Kaposis sarcoma no cases; 13 patients with lymphomas and other blood malignancies no cases; 600 pregnant women 1.5%; and 9 infants born to HIV-positive mothers 66%. These rates are in dramatic contrast with the high HIV seroprevalence rates in neighboring countries such as Zaire Central African Republic and the Congo among the general population and blood donors. More research is needed to assess the relative influence of social cultural genetic and environmental factors and sexual behavior on the variations in prevalence of HIV infection in African countries. A puzzling finding in this research is the higher rate of seropositivity among pregnant women in Cameroon (1.5%) than blood donors (0.28%). Overall it appears that Cameroon is a pre-epidemic area for acquired immunodeficiency syndrome (AIDS) and that preventive measures can stop or at least slow the spread of infection. |
| Databáze: | OpenAIRE |
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