2-(Ethoxycarbonylmethyl)-1H-naphtho[1,8-de]-1,2,3-triazine anion: a new glycine enolate equivalent

Autor:	Sosale Chandrasekhar, Malayalam Sridhar, R. Anilkumar
Rok vydání:	2000
Předmět:	chemistry.chemical_classification Aluminium amalgam fungi Organic Chemistry food and beverages Halide engineering.material Alkylation Biochemistry Medicinal chemistry Amino acid chemistry.chemical_compound chemistry Drug Discovery Glycine engineering Organic chemistry Moiety Alkyl Triazine
Zdroj:	Tetrahedron Letters. 41:6665-6668
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)01115-1
Popis:	The titled triazine can be alkylated with LDA and a variety of alkyl halides: subsequent reduction with aluminium amalgam cleaves the naphthotriazine moiety to afford substituted α amino acids in excellent overall yields; the sequence defines a novel methodology that can be applied under non-acidic and largely non-aqueous conditions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::69b331f4851adc4499544d32e3f0c2d2 https://doi.org/10.1016/s0040-4039(00)01115-1 Zobrazit plný text záznamu Full Text from ScienceDirect