A note on the power prior

Autor: Michael Branson, David Spiegelhalter, Beat Neuenschwander
Rok vydání: 2009
Předmět:
Zdroj: Statistics in Medicine. 28:3562-3566
ISSN: 0277-6715
DOI: 10.1002/sim.3722
Popis: The power prior by Ibrahim and Chen (Statist. Sci. 2000; 15:46–60) is one of several methods to incorporate historical data in the analysis of a clinical trial. The power prior raises the likelihood of the historical data to the power parameter a0 which quantifies the discounting of the historical data due to heterogeneity between trials. It is shown that the standard method of estimating the power parameter from the historical and current data is inappropriate, and we therefore suggest to use a modified power prior approach or to consider alternative methods instead. Copyright © 2009 John Wiley & Sons, Ltd.
Databáze: OpenAIRE