Hypothesis: Studies on Human Platelets III. A Contractile Protein Model for Platelet Aggregation

Autor:	Max E. Rafelson, F. M. Booyse
Rok vydání:	1969
Předmět:	Platelet aggregation Chemistry Immunology macromolecular substances Cell Biology Hematology medicine.disease Contractile protein Biochemistry Myosin medicine Biophysics Platelet Thrombus Actin
Zdroj:	Blood. 33:100-103
ISSN:	1528-0020 0006-4971
DOI:	10.1182/blood.v33.1.100.100
Popis:	A new hypothesis is proposed for platelet aggregation. The model involves the formation of intermolecular platelet actomyosin bridges between platelet actin and platelet myosin moieties localized on or near the surface of adjacent platelets. These intermolecular platelet actomyosin bridges can then contract in the presence of ATP, drawing the platelets into a tight mass or thrombus.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::69b08f5937fdfc5b7d96707d8492f5bc https://doi.org/10.1182/blood.v33.1.100.100 Zobrazit plný text záznamu