Effect of gnotobiotic conditions on the histophysiology of liver and spleen tissues
| Autor: | V. A. Lopatin, M. L. Finkel, V. V. Barannikov, O. V. Terekhov |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
medicine.medical_specialty
biology Succinate dehydrogenase Acid phosphatase Spleen General Medicine General Biochemistry Genetics and Molecular Biology Excretion Endocrinology medicine.anatomical_structure Biochemistry Cytoplasm Internal medicine Nonspecific esterase medicine biology.protein Liberation Fatty infiltration |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 85:95-98 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf00801467 |
| Popis: | The liver and spleen of gnotobiotic Wistar rats were studied by histochemical methods and the liver electron-microscopically. Under germfree conditions of existence of the animal the succinate dehydrogenase and nonspecific esterase activity in the liver decreased, fatty infiltration of the cytoplasm of the hepatocytes and Kupffer cells increased, and some of the cells developed fatty degeneration. Meanwhile acid phosphatase activity and the number of lysosomes increased in the biliary poles of the hepatocytes, whereas in the spleen destruction of erythrocytes and the liberation of free iron and pigments, which stimulate the excretion of bile in germfree animals, were increased. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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