Maternal Serum Vascular Endothelial Growth Factor in Patients with Preeclampsia
| Autor: | M Elsokkary, Mona Mohamed Soliman Elaassar, Tamer A. El-Refaie, Noha Bassiouny Hassan Mostafa |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Placental growth factor
medicine.medical_specialty 030219 obstetrics & reproductive medicine business.industry Obstetrics Gestational age medicine.disease Preeclampsia Clinical trial Vascular endothelial growth factor 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine chemistry Obstetrics and gynaecology Medicine Gestation Outpatient clinic 030212 general & internal medicine business reproductive and urinary physiology |
| Zdroj: | The Egyptian Journal of Hospital Medicine. 69:1634-1640 |
| ISSN: | 1687-2002 |
| Popis: | Background: Vascular endothelial growth factor and placental growth factor levels were significantly lower in patients of sever or early onset (34 weeks or less gestational age at onset of PET) pre-eclampsia than in controls. Aim of the Work:Will there be a rise in serum vascular endothelial growth factor in pregnant women suffering from preeclampsia than in normotensive pregnant women. Patients and Methods: 150 pregnant women from 28 weeks of gestation till term will be enrolled into this comparative clinical trial at the time of their antenatal visit to the outpatient department of obstetrics and gynecology Ain Shams University maternal hospital. Results: We recruited 150 pregnant women after 28 weeks of gestation and they were classified into 3 groups: Group1:50 pregnant women with mild preeclampsia from 28 weeks of gestation till term, Group2: 50 pregnant women with severe preeclampsia from 28 weeks of gestation till term and Group 3: 50 normal pregnant women serving as controls. Conclusion: We conclude that serum VEGF level measured after 28 weeks of gestation can be used as a predictor for preeclampsia and its degrees (mild and severe) with high sensitivity and specificity. |
| Databáze: | OpenAIRE |
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