Mechanism of in vitro reaction of a new scaffold ceramic similar to porous bone
| Autor: | Patricia Mazón, Anabel Díaz-Arca, Pablo Velasquez, P.N. De Aza |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
010302 applied physics
Scaffold Materials science Precipitation (chemistry) Simulated body fluid 02 engineering and technology Microporous material equipment and supplies 021001 nanoscience & nanotechnology Microstructure 01 natural sciences Chemical engineering visual_art Phase (matter) 0103 physical sciences Materials Chemistry Ceramics and Composites visual_art.visual_art_medium Ceramic 0210 nano-technology Porosity |
| Zdroj: | Journal of the European Ceramic Society. 40:2200-2206 |
| ISSN: | 0955-2219 |
| DOI: | 10.1016/j.jeurceramsoc.2020.01.045 |
| Popis: | A new way of obtaining bioactive and biodegradable 3D scaffold ceramics is presented with possible bone tissue engineering requests. This implies achieving eutectoid structures from certain systems by considering the different conduct of phases. In this study, the silicocarnotite-tricalcium phosphate subsystem was selected because silicocarnotite is bioactive and tricalcium phosphate is biodegradable. A biphasic porous calcium silicophosphate scaffold with high porosity and an interconnected macro- and micropores structure is presented. The scaffold’s morphology shows a eutectoid lamellae-type microstructure formed of alternating silicocarnotite and α-tricalcium phosphate layers. The eutectoid scaffold material, when placed in simulated body fluid, responds firstly by dissolving the silicocarnotite phase and then developing a hydroxyapatite microporous structure by pseudomorphic transformation of α-tricalcium phosphate lamellae. The achieved microstructure is like that of porous bone. Afterwards, Si-hydroxyapatite precipitation formed a layer on the scaffold surface by plugging the microporous structure and maintaining the scaffold’s 3D structure intact. |
| Databáze: | OpenAIRE |
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