Regiospecific biotransformation of substituted norbornanones by microorganisms
| Autor: | Helen Sandey, Andrew Willetts, Melissa S. Levitt |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
chemistry.chemical_classification
biology Stereochemistry Chemistry Microorganism Synthon Pseudomonas Bioengineering General Medicine biology.organism_classification Applied Microbiology and Biotechnology Substrate concentration chemistry.chemical_compound Biotransformation Pseudomonadales Organic chemistry Cyclopentane Lactone Biotechnology |
| Zdroj: | Biotechnology Letters. 12:197-200 |
| ISSN: | 1573-6776 0141-5492 |
| DOI: | 10.1007/bf01026798 |
| Popis: | The regiospecific biotransformation of (±) 5-acetoxy-7-fluoronorbornan-2-one into the equivalent bridgehead lactone of use as a source of substituted cyclopentane synthons containing four successive chiral centres has been demonstrated using washed-cell suspensions of cyclohexanol-grownAcinetobacter sp NCIB 9871. Conditions to optimise production of such 2-oxabicyclooctanones (substrate concentration |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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