Tracer flows and 'difficult' organs
Autor: | M. D. Rutland, L. Que |
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Rok vydání: | 1995 |
Předmět: |
Pathology
medicine.medical_specialty Cirrhosis medicine.diagnostic_test business.industry Hepatocellular damage chemistry.chemical_element Histology General Medicine medicine.disease Scintigraphy Technetium Gastroenterology Liver disease chemistry Internal medicine Medicine Radiology Nuclear Medicine and imaging In patient Uptake rate business |
Zdroj: | Nuclear Medicine Communications. 16:31-37 |
ISSN: | 0143-3636 |
DOI: | 10.1097/00006231-199501000-00007 |
Popis: | The hepatic uptake rate of sulphur or tin colloid was measured in the fasting state in patients who were later identified as belonging to one of three groups: normal, parenchymal liver disease or cirrhosis. Subsequent analysis showed a progressive decline in the hepatic uptake rate of tracer as the severity of hepatocellular damage increased. In particular, there was a positive correlation between the impairment of tracer uptake, and Childs' class A, B or C in the cirrhotic patients. In addition, a very low hepatic uptake rate of tracer was almost as good (80% accuracy) as Child's class C (83% accuracy) in identifying patients likely to die of hepatocellular problems within a year. When compared with needle biopsies or histology, the uptake rate usually proved equally accurate in indicating the severity of diffuse hepatocellular disease, and on occasions it was a better indicator of long-term outcome. |
Databáze: | OpenAIRE |
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