Tracer flows and 'difficult' organs

Autor: M. D. Rutland, L. Que
Rok vydání: 1995
Předmět:
Zdroj: Nuclear Medicine Communications. 16:31-37
ISSN: 0143-3636
DOI: 10.1097/00006231-199501000-00007
Popis: The hepatic uptake rate of sulphur or tin colloid was measured in the fasting state in patients who were later identified as belonging to one of three groups: normal, parenchymal liver disease or cirrhosis. Subsequent analysis showed a progressive decline in the hepatic uptake rate of tracer as the severity of hepatocellular damage increased. In particular, there was a positive correlation between the impairment of tracer uptake, and Childs' class A, B or C in the cirrhotic patients. In addition, a very low hepatic uptake rate of tracer was almost as good (80% accuracy) as Child's class C (83% accuracy) in identifying patients likely to die of hepatocellular problems within a year. When compared with needle biopsies or histology, the uptake rate usually proved equally accurate in indicating the severity of diffuse hepatocellular disease, and on occasions it was a better indicator of long-term outcome.
Databáze: OpenAIRE