Pulmonary vein isolation for paroxysmal atrial fibrillation using high-power short duration radiofrequency or second-generation cryoballoon ablation
| Autor: | T Major, Zoltán Som, Zsófia Brigitta Nagy, Attila Kardos, K Kassa, L Csakany, Csaba Földesi, D Simkovits, Zsuzsanna Kis |
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| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Ejection fraction business.industry Paroxysmal atrial fibrillation medicine.medical_treatment Ablation Pulmonary vein Physiology (medical) Internal medicine medicine Cardiology Sinus rhythm medicine.symptom Cardiology and Cardiovascular Medicine business Short duration Atrial tachycardia Cryoballoon ablation |
| Zdroj: | EP Europace. 23 |
| ISSN: | 1532-2092 1099-5129 |
| DOI: | 10.1093/europace/euab116.248 |
| Popis: | Funding Acknowledgements Type of funding sources: None. Background Differences in the left atrial (LA) tissue loss can occur following different pulmonary vein isolation (PVI) techniques. Purpose Our prospective study compared the biomarker, the LA mechanical, and the electrophysiological findings as indicators of LA myocardial damage after a high-power short duration (HPSD) with contact force radiofrequency catheter and second-generation cryoballoon (CB2) ablation of paroxysmal atrial fibrillation (AF). Methods :We enrolled 40 patients with paroxysmal AF [16 (40%) women, mean age = 55.9 ± 12.4 years] who underwent HPSD (n = 21) or CB2 (n = 19). Biomarker levels (hs-cTnT, CK-MB, hs-CRP, LDH) and the transport function of the LA by transthoracic echocardiography (TTE) were compared pre and post procedurally. High-density mapping (HDM) was performed in sinus rhythm using a multielectrode diagnostic catheter in each group to define isolated left atrial low voltage area (LVA; Results Postablation hs-cTnT and hs-CRP levels were comparable in the ablation groups (HPSD: 1249 ± 469 and 9.53 ± 10.30 vs. CB2: 995 ± 280 and 12.36 ± 5.76, p = 0.065 and p = 0.732), while CK-MB and LDH levels were significantly higher following CB2 ablation (HPSD: 6.61 ± 2.62 and 349.9 ± 65.6 vs. CB2: 26.01 ± 6.88 and 451.6 ± 91.3, p Conclusions The LA scar tissue was significantly higher following CB2 ablation, but did not affect medium-term efficacy. However, tissue loss did not reduce the transport function of the LA. |
| Databáze: | OpenAIRE |
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