Determinants of Poor Outcome after Intracerebral Hemorrhage: Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) Study

Autor: Christopher D. Anderson, Sebastian Koch, Christiana E. Hall, Jennifer Osborne, Carl D. Langefeld, Misty Wethington, Daniel Woo, Michael L. James, Jacob L. McCauley, Lee Birnbaum, Bruce M. Coull, Fernando D. Testai, Lee A Gilkerson, Bradford B. Worrall, Kevin N. Sheth, Michael Frankel, Charles J Moomaw, Gene Sung, Chelsea S. Kidwell, Mary E. Comeau, Simone M. Uniken Venema, Padmini Sekar, Marc D. Malkoff, Nicole R. Gonzales, Jonathan Rosand, Douglas Mayson, Elisheva R Coleman, Steven J. Kittner, Mitchell S.V. Elkind, Matthew L. Flaherty, Tyler P Behymer
Rok vydání: 2019
Předmět:
Zdroj: SSRN Electronic Journal.
ISSN: 1556-5068
DOI: 10.2139/ssrn.3444426
Popis: Introduction: Intracerebral hemorrhage (ICH) is the most severe subtype of stroke. Its mortality rate is high, and the majority of survivors suffer significant disability. The Ethnic/Racial Variations of Intracerebral Hemorrhage (ERICH) study prospectively recruited 1000 non-Hispanic white, 1000 non-Hispanic black, and 1000 Hispanic spontaneous ICH cases to study the epidemiology and genomics of ICH. Herein, we report the primary determinants of 3-month outcome after ICH in a large, multi-ethnic cohort. Methods: Between 2010 and 2015, cases were prospectively recruited with uniform data collection and phenotype definitions, centralized neuroimaging review, and telephone follow-up at 3 months. Individual characteristics were screened for association with 3-month outcome of modified Rankin Scale (mRS) ≥4 versus ≤3 under a logistic regression model, and those meeting P
Databáze: OpenAIRE